Does Estrogen Diminish TMJ Pain?

The typical profile of patients with TM Disorders is of women in their child-bearing years. This means that they undergo fluctuating levels of estrogen in the bloodstream, depending upon the phase of the menstrual cycle, with estrogen levels highest near ovulation.

Researchers studying an experimental TMJ pain model in rats have noted that pain in these female animals appears to be reduced in the pre-ovulatory phase when estrogen levels are highest.

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